Sleep deprivation and other sleep disorders can have a serious effect on health

Sleep problems may affect performance at work and quality of life, as well as have an impact on some chronic diseases

Insomnia and disruption of the sleep-wake cycle start a cascade of events that involve different organs, and have been associated with a wide range of deleterious health consequences, including an increased risk of hypertension, diabetes and obesity: an early identification of patients with sleep problems and an optimal treatment planning and management have a major influence on the patient’s physical and mental condition.

Milan, March 16, 2018 – Approximately 4 out of 5 diabetic patients and 2 out of 5 hypertensive patients show symptoms of insomnia. Findings from recent studies have demonstrated the close relationship between sleep disorders and cardiometabolic diseases, such as hypertension and type II diabetes. According to these studies, diabetes is a major comorbid condition in sleep-deprived individuals , and people suffering from sleep disorders have a higher risk of developing hypertension, namely 300-500% higher with respect to non-insomniacs (independently of age, body mass index, diabetes, alcohol consumption, and smoking).

Such work has led to further confirmation of the key role exerted by sleep in maintaining a good mental and physical health: changes in the so-called internal clock may also have an impact on other crucial physiological functions, such as hormone levels, body temperature, blood pressure, mood, and energy metabolism – says Prof. Lino Nobili, Scientific Coordinator of the Sleep & Health Project, (Progetto Sonno & Salute), Secretary of the European Sleep and Research Society and Head of the Centre of Sleep Medicine, Niguarda Hospital, Milan, Italy - Sleep disturbances, hypertension and diabetes are frequently associated with lower secretion of melatonin, a naturally occurring hormone mainly released by the pineal gland in the head, that regulates circadian rhythm and maintains the internal clock balanced within a 24-hour schedule. Besides regulating the sleep-wake cycle, melatonin plays a decisive role in modulating energy and glucose metabolism over 24 hours. In addition, by influencing the circadian rhythm – hence, blood pressure - melatonin may also affect the cardiovascular system.”

Based on this evidence, and thanks to the contribution of the Italian pharma company Fidia Farmaceutici, the second edition of the Sleep & Health Project (Progetto Sonno & Salute) will be launched this month, focusing on the cardiometabolic comorbidities of insomnia. Starting March 24, 2018, 18 CME courses will take place throughout Italy, involving local GPs and specialists (cardiologists, endocrinologists, geriatric physicians, diabetologists, neurologists, internists, and psychiatrists).

The “Sleep & Health” Project 2018 focuses on the cardiometabolic comorbidities of insomnia, and si dedicated to GPs and specialists (cardiologists, endocrinologists, geriatric physicians, diabetologists, neurologists, internists, and psychiatrists).


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