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Skin care

We are committed in the treatment of acute and chronic lesions ranging from low to high risk of infection: up to the restoration of the skin barrier for the skin’s well-being.

Wounds are estimated to account for almost 3% of total health system costs.1
Any tissue injury with an anatomical integrity disruption and a loss of functionality can be described as a wound. A skin wound results from the breakdown of the epidermal layer integrity. When we talk about wound healing, we mostly mean the healing of the skin. The wound healing begins immediately after an injury to the epidermal layer and might last for years. This dynamic process includes the highly organized cellular, humoral and molecular mechanisms. Wound healing has four overlapping phases which are hemostasis, inflammation, proliferation, and remodelling.2 Wound healing has 3 overlapping phases which are inflammation, proliferation, and remodelling. Any disruption during these phases leads to abnormal wound healing.3

1 Lindholm C, Searle R. Wound management for the 21st century: combining effectiveness and efficiency. Int Wound J. 2016;13 Suppl 2(Suppl 2):5-15.
2Wound Healing And Repair: Overview, Types Of Wound Healing, Categories Of Wound Healing”. Emedicine.Medscape.Com, 2022
3Ozgok Kangal MK, Regan JP. Wound Healing. StatPearls 2021

Prevention of infection is crucial for the wound-healing process.
Infection is the n.1 complication of wound healing.
Once skin is injured, micro-organisms that are normally sequestered at the skin surface obtain access to the underlying tissues. Inflammation is a normal part of the wound-healing process and is important to the removal of contaminating micro-organisms. In the absence of effective decontamination, however, inflammation may be prolonged since microbial clearance is incomplete. If this continues, the wound may enter a chronic state and fail to heal.1 That’s why it is important to prevent infections in any type of skin wounds. Signs of an infected wound include redness, swelling, pain, local warmth, purulent discharge, abscess, malodour, pyrexia and delayed healing. If the patient shows any of these signs a consultation with his health care provider is recommended since various health complications can be caused by the spread of the infection.2
1 Guo S, Dipietro LA. Factors affecting wound healing. J Dent Res. 2010
2 Wound infection in clinical practice. An international consensus. Int Wound J. 2008

Up to 2 million people live with a chronic wound across Europe.1
In the USA, chronic wounds affect around 6.5 million people at any one time.1
Chronic wound is a wound that has failed to heal for a time span related to chronicity that has been defined in the range 4 weeks up to more than 3 months. Based on the causative aetiologies, the Wound Healing Society classifies chronic wounds into four categories: pressure ulcers, diabetic ulcers, venous ulcers and arterial insufficiency ulcers. Traumatic wounds, surgical incisions and burns can also turn into chronic wounds.2
Often disguised as a comorbid condition, chronic wounds represent a silent epidemic that affects a large fraction of the world population. Complications of chronic wounds include infection such as cellulitis and infective venous eczema, gangrene, haemorrhage and lower-extremity amputations. Chronic wounds lead to disability and disability worsens wound outcomes resulting in a vicious cycle.3
1 Lindholm C, Searle R. Wound management for the 21st century: combining effectiveness and efficiency. Int Wound J. 2016;13 Suppl 2(Suppl 2):5-15.
2Better health channel. Wounds – how to care for them. (https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/wounds-how-to-care-for-them)
3 Järbrink, K., Ni, G., Sönnergren, H. et al. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. Syst Rev 5,2016

CHRONIC WOUNDS
3% of total health system costs
INFECTION
N. 1 complication of wound healing
LIVE WITH A CHRONIC WOUND
Up to 2 million people in Europe
Our Brands
HYALO4 care product line
HY-TISSUE product line

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